Effects of stereotactic neurosurgery on postural instability and gait in Parkinson's disease
Identifieur interne : 001645 ( Main/Exploration ); précédent : 001644; suivant : 001646Effects of stereotactic neurosurgery on postural instability and gait in Parkinson's disease
Auteurs : Maaike Bakker [Pays-Bas] ; Rianne A. J. Esselink [Pays-Bas] ; Marten Munneke [Pays-Bas] ; Patricia Limousin-Dowsey [Royaume-Uni] ; Hans D. Speelman [Pays-Bas] ; Bastiaan R. Bloem [Pays-Bas]Source :
- Movement Disorders [ 0885-3185 ] ; 2004-09.
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Abstract
Postural instability and gait disability (PIGD) are disabling signs of Parkinson's disease. Stereotactic surgery aimed at the internal globus pallidus (GPi) or subthalamic nucleus (STN) might improve PIGD, but the precise effects remain unclear. We performed a systematic review of studies that examined the effects of GPi or STN surgery on PIGD. Most studies examined the effects of bilateral GPi stimulation, bilateral STN stimulation, and unilateral pallidotomy; we, therefore, only performed a meta‐analysis on these studies. Bilateral GPi stimulation, bilateral STN stimulation, and to a lesser extent, unilateral pallidotomy significantly improved PIGD, and more so during the ON phase than during the OFF phase. © 2004 Movement Disorder Society
Url:
DOI: 10.1002/mds.20116
Affiliations:
- Pays-Bas, Royaume-Uni
- Angleterre, Grand Londres, Gueldre, Hollande-Septentrionale
- Amsterdam, Londres, Nimègue
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Bilateral GPi stimulation, bilateral STN stimulation, and to a lesser extent, unilateral pallidotomy significantly improved PIGD, and more so during the ON phase than during the OFF phase. © 2004 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>Pays-Bas</li><li>Royaume-Uni</li></country><region><li>Angleterre</li><li>Grand Londres</li><li>Gueldre</li><li>Hollande-Septentrionale</li></region><settlement><li>Amsterdam</li><li>Londres</li><li>Nimègue</li></settlement></list><tree><country name="Pays-Bas"><region name="Gueldre"><name sortKey="Bakker, Maaike" sort="Bakker, Maaike" uniqKey="Bakker M" first="Maaike" last="Bakker">Maaike Bakker</name></region><name sortKey="Bloem, Bastiaan R" sort="Bloem, Bastiaan R" uniqKey="Bloem B" first="Bastiaan R." last="Bloem">Bastiaan R. Bloem</name><name sortKey="Esselink, Rianne A J" sort="Esselink, Rianne A J" uniqKey="Esselink R" first="Rianne A. J." last="Esselink">Rianne A. J. 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